• DNA replication checkpoint kinases in both yeast

  2021-02-26

  

  DNA replication checkpoint kinases in both yeast and human Loxapine Succinate upregulate dNTP levels under replication stress to mediate their essential function at replication forks (Yeeles et al., 2013). It is possible that upregulation of dNTP levels under replication stress helps fork restart o

• br Material and methods br Results and discussion

  2021-02-26

  

  Material and methods Results and discussion Conclusions Acknowledgements S. De thanks DST, New Delhi for generous grant of the SERC Fast Track Scheme No. SR/FT/CS-057/2008. R. Kundu thanks the University of Kalyani for financial assistance. We are grateful to Prof. K. Bhattacharyya of IA

• Collectively the results presented here provide new insights

  2021-02-26

  

  Collectively, the results presented here provide new insights into ligand binding, clustering, spatial distribution, and phosphorylation of DDR1b and DDR2 in response to soluble collagen I. As depicted in the cartoon of Scheme 1, we postulate a model in which the spatial distribution and assembly of

• br Materials and methods br

  2021-02-26

  

  Materials and methods Results Discussion In this study, we developed a new CysLT1 and CysLT2 receptors-mediated GSK2656157 guinea pig model for screening both CysLT2 receptor and CysLT1/2 receptor antagonists. Unlike human CysLT2 receptors, which are equally stimulated by both LTC4 and LTD

• The identification of a functional leucine rich NES mediatin

  2021-02-26

  

  The identification of a functional leucine-rich NES mediating 8E7 nuclear export led us to analyze the interaction between 8E7 and CRM1 nuclear export receptor. HeLa cell lysates containing EGFP-8E7, EGFP–8cE7, EGFP-16E7–NES (as a positive control), or EGFP (as a negative control) were incubated wit

• This work aimed to investigate whether the

  2021-02-26

  

  This work aimed to investigate whether the increase in liver lipid depots, observed in the fetuses from rats fed a saturated-fat-rich diet, persists later in life in the offspring (a) at 21days of age immediately after weaning and (b) at 140days of age, after healthy nourishing. Furthermore, we want

• Placental insufficiency is regarded as

  2021-02-26

  

  Placental insufficiency is regarded as the main etiology for FGR. Placental development is highly unique in eutherians and is regulated by numerous factors. For example, the novel retrotransposon-derived gene retrotransposon-like 1 (RTL1) was recently shown to play a key role in placental developmen

• The radial distribution function is given by

  2021-02-26

  

  The radial distribution function, , is given by: For pure components and pseudo-components, the constants a and b are calculated as:whereand Tc, Pc and ω are the critical temperature, critical pressure and acentric factor, respectively. Parameters a and b for mixtures are calculated from those of

• Another significant finding in our study was the demonstrati

  2021-02-26

  

  Another significant finding in our study was the demonstration that the axon-protective action associated with CK2 inhibition correlated with preservation of mitochondrial structure and function in orexin receptor (Fig. 11). Because of the consistent protection conferred by CK2 inhibition during OG

• Although CK phosphorylated Msn as well as Msn Fig

  2021-02-26

  

  Although CK2 phosphorylated Msn4 as well as Msn2 (Fig. 1A), the two CK2-dependent phosphorylation sites in Msn2 are not conserved in Msn4. Thus, Msn2 and Msn4 might be differently regulated by CK2-dependent phosphorylation. Msn2 and Msn4, which have 41% identity and similarity in size and amino BCAT

• br Conclusion In this review we have discussed how

  2021-02-26

  

  Conclusion In this review, we have discussed how inhibition of the CK2/CDK5 signaling axis protects WM only when inhibited before ischemia, while inhibition of the CK2/AKT/GSK3β signaling axis protects WM either before or after an ischemic injury in young, aging, and old WM (Fig. 3). CK2 activati

• is one of the few parasites

  2021-02-26

  

  is one of the few parasites that can be encysted and excysted and we tested the localization and role of HA-tagged gEno in both differentiations, using a recently developed integrated vector that introduces a C-terminal triple HA tag under the selection marker puromycin . The localization of HA-ta

• The mitogen activated protein kinase MAPK family

  2021-02-26

  

  The mitogen-activated protein kinase (MAPK) family, which consists of extracellular signal-regulated protein kinase 1/2 (ERK1/2), p38 MAPK, and c-Jun N-terminal kinase (JNK), is involved in the development of NP (Hung et al., 2012, Ji et al., 2009). Recently, Zhuang et al. (2005) demonstrated that t

• Finally we have determined for the first time that aromatase

  2021-02-26

  

  Finally, we have determined for the first time that aromatase enzyme activity is necessary to observe IGF-1-dependent fluvastatin receptor activation. Neuroestrogen synthesis has been shown to be important for the maintenance of synaptic spine density in hippocampal slice cultures (Kretz et al., 20

• Compression The L vertebral body

  2021-02-26

  

  Compression: The L4 vertebral body was tested in compression with loads applied along the craniocaudal axis using an Instron 8800 device at a rate of 3mm/min. Load displacement data were captured using Bluehill software. The ultimate load, yield load, stiffness, ultimate stress, yield stress and You

10864 records 376/725 page Previous Next First page 上5页 376377378379380 下5页 Last page