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In conclusion a rare KCNE D N polymorphism may modify
2019-05-23

In conclusion, a rare KCNE1-D85N polymorphism may modify the LQTS phenotype in combination with other pathogenic LQTS-related gene mutations. Disclosures Conflict of interest Acknowledgments Introduction Atrial fibrillation (AF) is observed in 10–30% of patients with symptomatic order n
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Several anti platelet therapies have been evaluated in the
2019-05-23

Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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Este autor nos permite la oportunidad de reflexionar
2019-05-23

Este autor nos permite la oportunidad de reflexionar la presencia de los sujetos colectivos a la hora de elaborar proyectos ético-políticos de la llamada “sociedad por venir”. Por ejemplo, cabe destacar en sus propuestas la preocupación sobre la justicia de las personas y de los colectivos desde la
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Muy a pesar de que ambos documentos de la Congregaci
2019-05-23

Muy Silvestrol pesar de que ambos documentos de la Congregación para la Doctrina de la Fe citaban repetidamente el documento conclusivo de la reunión de la conferencia del celam en Puebla -que no la de Medellín—, la postura de Ratzinger evidenció el criterio hegemónico enunciado desde una perspectiv
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Esta parte de la cr tica a la
2019-05-23

Esta parte de la crítica a la que aludo, en aquel entonces, se orienta hacia el replanteamiento de la función social de la literatura y el cuestionamiento epistemológico de la práctica crítica misma. Incidiendo en este aspecto, George Gugelberger llega a afirmar lo siguiente: “Thus, the testimonio b
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Countdown to concluded its tasks after the launch
2019-05-23

Countdown to 2015 concluded its tasks after the launch of its seventh global report at the Maternal Newborn Health conference in Mexico City, October, 2015. It is now relaunched as Countdown to 2030 (CD2030), retaining and enhancing the successful multi-institutional network with over a decade of he
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br Discussion Catheter ablation has played an
2019-05-22

Discussion Catheter ablation has played an increasingly important role in controlling VT episodes in patients with structural rac1 inhibitor disease who have an ICD [6–10]. LPs recorded at an endocardial ventricular site reflect slow conduction into a protected zone. Strategies for the successfu
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Arita et al reported that the mechanism of ST
2019-05-22

Arita et al. reported that the mechanism of ST-segment elevation in inferior leads is right coronary artery hypoperfusion due to vasodilation by Bezold–Jarisch-like reflexes that are induced by stimulation of the notch signaling in the intra-atrial septum during transseptal puncture and extension [
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The acute effects of goserelin on
2019-05-22

The acute effects of goserelin on bone have also been evaluated by prospective trials of goserelin+/− adjuvant tamoxifen. The Zoladex in Premenopausal Patients trial randomized 89 women with early breast cancer to goserelin+/− tamoxifen, tamoxifen alone and no endocrine therapy. After 2 years of tre
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Performing an ajmaline test in children is problematic for r
2019-05-22

Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri
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Unfortunately no trends in retention in care were presented
2019-05-22

Unfortunately, no trends in retention in care were presented by Nsanzimana and colleagues, and the method used to estimate life expectancy—the abridged life table method—is not well suited to answering questions about trends in quality of care, because it BAY 87-2243 allows little scope for multiva
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br Conflict of interest br Introduction Bladder
2019-05-22

Conflict of interest Introduction Bladder cancer is one of the most common cancers in the world. It is estimated that around 74,000 new cases of reductase enzyme cancer and 16,000 bladder cancer-related deaths will occur in the United States in 2015. It is prominent in men and in the elderly
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br Discussion Metastatic RCC is a fatal disease
2019-05-22

Discussion Metastatic RCC is a fatal disease with survival often measured in months, rather than years. Surgery alone is the standard of care for patients who present with isolated renal disease at the time of diagnosis. However, approximately 1/3 of these patients will go on to develop clinicall
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The PPI from the CS ostium was close to
2019-05-22

The PPI from the CS ostium was close to the TCL, suggesting that the CS ostium was on the dominant circuit (Fig. 8B). During entrainment from the CS ostium, the last captured beat of the TA was the second beat after the stimulus, suggesting that the slow conduction area (crosshatch) was located dist
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WEHI-539 To date over mutations in KCNQ have been found to
2019-05-22

To date, over 250 mutations in KCNQ1 have been found to be linked to LQT1 [34] and new LQT1 causing mutations continue to be identified. The vast majority of KCNQ1 mutations are single nucleotide substitutions (missense) or small insertion/deletions that localize to the S1-S6 transmembrane domains [
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